METTL3 antibody

Catalog No. ABIN2461900

This Rabbit Polyclonal antibody specifically detects METTL3 in WB, IHC and ELISA. It exhibits reactivity toward Human, Rat, Mouse, Dog and Zebrafish (Danio rerio).

Quick Overview for METTL3 antibody (ABIN2461900)

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Reactivity: Human, Rat, Mouse, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-METTL3 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human METTL3.

Application Details

Application Notes: METTL3 antibody can be used for detection of METTL3 by ELISA at 1:312500. METTL3 antibody can be used for detection of METTL3 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store METTL3 antibody at -20 °C.

Target Details for METTL3

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Alternative Name: METTL3

Background: METTL3 is the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

Molecular Weight: 64 kDa

Gene ID: 56339

NCBI Accession: NP_062826

UniProt: Q86U44