SLC13A3 antibody

Catalog No. ABIN2462408

The Rabbit Polyclonal anti-SLC13A3 antibody is suitable to detect SLC13A3 in samples from Human, Dog, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for SLC13A3 antibody (ABIN2462408)

Target: SLC13A3 (Solute Carrier Family 13 Member 3 (SLC13A3))

Reactivity: Human, Dog, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC13A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SLC13A3 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC13A3.

Application Details

Application Notes: SLC13A3 antibody can be used for detection of SLC13A3 by ELISA at 1:12500. SLC13A3 antibody can be used for detection of SLC13A3 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SLC13A3 antibody at -20 °C.

Target Details for SLC13A3

Target: SLC13A3 (Solute Carrier Family 13 Member 3 (SLC13A3))

Alternative Name: SLC13A3

Background: Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. SLC13A3 represents the high-affinity form.Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.

Molecular Weight: 66 kDa, 62 kDa

Gene ID: 64849

NCBI Accession: NP_073740

UniProt: Q8WWT9

Pathways: Dicarboxylic Acid Transport