FECH antibody

Catalog No. ABIN2462452

This Rabbit Polyclonal antibody specifically detects FECH in WB and ELISA. It exhibits reactivity toward Human, Mouse, Rat and Dog.

Quick Overview for FECH antibody (ABIN2462452)

Target: FECH (Ferrochelatase (FECH))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FECH antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FECH Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FECH.

Application Details

Application Notes: FECH antibody can be used for detection of FECH by ELISA at 1:1562500. FECH antibody can be used for detection of FECH by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FECH antibody at -20 °C.

Target Details for FECH

Target: FECH (Ferrochelatase (FECH))

Alternative Name: FECH

Background: Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria.Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 47 kDa, 48 kDa

Gene ID: 2235

NCBI Accession: NP_001012533

UniProt: Q8NAN0

Pathways: Transition Metal Ion Homeostasis