UPB1 antibody

Catalog No. ABIN2462585

The Rabbit Polyclonal anti-UPB1 antibody has been validated for WB and ELISA. It is suitable to detect UPB1 in samples from Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Drosophila melanogaster, Arabidopsis and C. elegans.

Quick Overview for UPB1 antibody (ABIN2462585)

Target: UPB1 (Ureidopropionase, beta (UPB1))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Drosophila melanogaster, Arabidopsis, C. elegans

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UPB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-UPB1 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UPB1.

Application Details

Application Notes: UPB1 antibody can be used for detection of UPB1 by ELISA at 1:1562500. UPB1 antibody can be used for detection of UPB1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store UPB1 antibody at -20 °C.

Target Details for UPB1

Target: UPB1 (Ureidopropionase, beta (UPB1))

Alternative Name: UPB1

Background: UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activityThis gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.

Molecular Weight: 42 kDa

Gene ID: 51733

NCBI Accession: NP_057411

UniProt: Q9UBR1