Bloom Syndrome (pSer186) antibody

Catalog No. ABIN2464128

This anti- antibody is a Rabbit Polyclonal antibody detecting in IHC, ELISA and WB. Suitable for Human, Mouse, Non-Human Primate and Rat.

Quick Overview for Bloom Syndrome (pSer186) antibody (ABIN2464128)

Target: Bloom Syndrome

Reactivity: Human, Mouse, Non-Human Primate, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Product Details

Binding Specificity: pSer186

Purification: Affinity Purified

Immunogen: A synthetic peptide surrounding amino acid S186.

Isotype: IgG

Application Details

Application Notes: ELISA, Western (immuno) blotting, Immunostaining (in testing)

Restrictions: For Research Use only

Handling

Target Details

Target: Bloom Syndrome

Background: The Bloom syndrome gene product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids, including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom's syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom's syndrome, namely cancer and diabetes.

Gene ID: 641

UniProt: P54132