Bloom Syndrome (pSer527) antibody
Reactivity: Human, Mouse, Non-Human Primate, Rat
IHC, ELISA, WB
Host: Rabbit
Polyclonal
unconjugated
-
- Target
- Bloom Syndrome
-
Binding Specificity
- pSer527
- Reactivity
- Human, Mouse, Non-Human Primate, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- Un-conjugated
-
Application
- Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
- Purification
- Affinity Purified
- Immunogen
- A synthetic peptide surrounding amino acid S527
- Isotype
- IgG
-
anti-Bloom Syndrome (AA 65-114), (pThr99) antibody
Reactivity: Human IHC, ELISA, WB, IF Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- ELISA, Western (immuno) blotting, Immunostaining (in testing)
- Restrictions
- For Research Use only
-
-
- Target
- Bloom Syndrome
- Background
- The Bloom syndrome gene product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids, including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom's syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom's syndrome, namely cancer and diabetes.
- Gene ID
- 641
- UniProt
- P54132
-
You are here:
