Tropomyosin antibody (Ser283)

Catalog No. ABIN2464143

This anti-Tropomyosin antibody is a Rabbit Polyclonal antibody detecting Tropomyosin in WB, ELISA and IHC. Suitable for Human, Rat, Mouse, Chicken and Non-Human Primate.

Quick Overview for Tropomyosin antibody (Ser283) (ABIN2464143)

Target: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Reactivity: Human, Rat, Mouse, Chicken, Non-Human Primate

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tropomyosin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Tropomyosin Antibody

Binding Specificity: Ser283

Purification: Affinity Purified

Immunogen: A synthetic phosphopeptide corresponding to the region surrounding S283.

Isotype: IgG

Application Details

Application Notes: ELISA, Western (immuno) blotting, Immunostaining (in testing)

Restrictions: For Research Use only

Handling

Target Details for Tropomyosin

Target: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Alternative Name: Tropomyosin-1a

Background: Tropomyosin (Tpm-1)consists of a family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction..

Gene ID: 7168

UniProt: P09493

Pathways: Regulation of Actin Filament Polymerization