TK1 antibody

Catalog No. ABIN2466869

The Mouse Monoclonal anti-TK1 antibody has been validated for WB and ELISA. It is suitable to detect TK1 in samples from Human.

Quick Overview for TK1 antibody (ABIN2466869)

Target: TK1 (Thymidine Kinase 1, Soluble (TK1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3B3-E11

Product Details anti-TK1 Antibody

Purification: Protein G-purified

Immunogen: 5 -His-tagged recombinant human thymidine kinase.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C

Storage Comment: Thymidine Kinase monoclonal antibody can be stored at 4 °C, stable for one year.

Target Details for TK1

Target: TK1 (Thymidine Kinase 1, Soluble (TK1))

Alternative Name: Thymidine Kinase

Background: Thymidine kinase (TK) belongs to a group of enzymes such as dihydrofolate reductase, thymidylate synthase, and DNA polymerase that are involved in DNA synthesis and precursor production. High levels of these enzymes are present in proliferating cells, and low levels are found in resting cells, due to multiple regulatory mechanisms that ensure exclusive expression of these enzymes in replicating cells. TK is responsible for catalyzing the phosphorylation of thymidine, which functions as a part of the pyrimidine salvage pathway involved in DNA synthesis. The activities of enzymes such as TK are essential for the activation of several chemotherapeutically important nucleoside analogues that are administered as prodrugs.

Gene ID: 3978

UniProt: P18858