alpha Fetoprotein antibody (AA 180-420)

Catalog No. ABIN2467766

The Chicken Polyclonal anti-alpha Fetoprotein antibody has been validated for WB. It is suitable to detect alpha Fetoprotein in samples from Human.

Quick Overview for alpha Fetoprotein antibody (AA 180-420) (ABIN2467766)

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivity: Human

Host: Chicken

Clonality: Polyclonal

Conjugate: This alpha Fetoprotein antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-alpha Fetoprotein Antibody

Binding Specificity: AA 180-420

Purification: Antigen affinity-purified

Application Details

Application Notes: AFP antibody can be used for the detection of AFP by Western blot, may also work for IHC and ICC.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Preservative: Without preservative

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Storage Comment: AFP antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Target Details for alpha Fetoprotein

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Alternative Name: AFP

Background: Alpha-1-fetoprotein. alpha-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Molecular Weight: 68.7 kDa (calculated)

Gene ID: 174

NCBI Accession: NP_001125

UniProt: P02771

Pathways: C21-Steroid Hormone Metabolic Process