Small inducible cytokine A4 antibody can be used for the detection of Small inducible cytokine A4 by ELISA and Western Blot, may also work for ICC and IHC.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate-Buffered Saline. No preservatives added.
Preservative
Without preservative
Handling Advice
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage
4 °C/-20 °C
Storage Comment
CCL4 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
Target
CCL4
(Chemokine (C-C Motif) Ligand 4 (CCL4))
Alternative Name
CCL4
Background
FUNCTION: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.