Caveolin-1 antibody (N-Term)

Catalog No. ABIN2469326

The Rabbit Polyclonal anti-Caveolin-1 antibody has been validated for IHC. It is suitable to detect Caveolin-1 in samples from Human, Rat, Mouse, Dog, Pig, Cow, Rabbit, Sheep, Monkey, Horse, Guinea Pig, Bat, Chimpanzee, Gibbon, Gorilla and Orang-Utan.

Quick Overview for Caveolin-1 antibody (N-Term) (ABIN2469326)

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Reactivity: Human, Rat, Mouse, Dog, Pig, Cow, Rabbit, Sheep, Monkey, Horse, Guinea Pig, Bat, Chimpanzee, Gibbon, Gorilla, Orang-Utan

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin-1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Caveolin-1 Antibody

Binding Specificity: N-Term

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: Caveolin - 1 antibody was raised against a peptide located in the N-Terminal region of Caveolin - 1 (Human).

Application Details

Application Notes: Caveolin-1 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, immunofluorescence starting at 10 μg/mL, and immunoprecipitation.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: Caveolin-1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for Caveolin-1

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Alternative Name: Caveolin-1

Background: Caveolin 1 is the main component of the caveolae plasma membranes found in most cell types. Caveolin 1 functions as a membrane adaptor to link integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 may also be a tumor suppressor gene and a negative regulator of the Ras-p42/44 MAP kinase cascade.

Gene ID: 857

UniProt: Q03135

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals