BACE1 antibody (Internal Region)

Catalog No. ABIN2469509

The Rabbit Polyclonal anti-BACE1 antibody has been validated for IHC. It is suitable to detect BACE1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Monkey, Pig, Bat, Hamster and Gibbon.

Quick Overview for BACE1 antibody (Internal Region) (ABIN2469509)

Target: BACE1 (Beta-secretase 1 (BACE1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Monkey, Pig, Bat, Hamster, Gibbon

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACE1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-BACE1 Antibody

Binding Specificity: Internal Region

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: BACE1 antibody was raised against a peptide located near the internal domain of BACE1 (Human).

Application Details

Application Notes: BACE1 antibody can be used in immunohistochemistry starting at 1:50.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: BACE1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for BACE1

Target: BACE1 (Beta-secretase 1 (BACE1))

Alternative Name: BACE1

Background: Bace 1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

Gene ID: 23621

UniProt: P56817