PSMA antibody (C-Term)

Catalog No. ABIN2470727

The Rabbit Polyclonal anti-PSMA antibody has been validated for IHC. It is suitable to detect PSMA in samples from Human.

Quick Overview for PSMA antibody (C-Term) (ABIN2470727)

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-PSMA Antibody

Binding Specificity: C-Term

Purification: Immunoaffinity Chromatography

Immunogen: FOLH1 antibody was raised against amino acids from the C-Terminus of FOLH1 (Human).

Application Details

Application Notes: FOLH1 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM PBS, pH 7.4, BSA, sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store FOLH1 antibody at 4 °C or -20 °C.

Target Details for PSMA

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Alternative Name: FOLH1

Background: PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including poly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate- specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.

Gene ID: 2346

UniProt: Q04609