C-Type Lectin Domain Family 6, Member A (CLEC6A) (Extracellular Domain) antibody

Catalog No. ABIN2473279

Product Details

Target: C-Type Lectin Domain Family 6, Member A (CLEC6A)

Binding Specificity: Extracellular Domain

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Immunogen: Dectin-2 (extracellular domain) Fc Fusion protein.

Clone: D2-11E4

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

References

Barrett, Rahman, Fernandez, Parsons, Xing, Austen, Kanaoka: "Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes." in: The Journal of experimental medicine, Vol. 208, Issue 3, pp. 593-604, (2011) (PubMed).

Suram, Gangelhoff, Taylor, Rosas, Brown, Bonventre, Akira, Uematsu, Williams, Murphy, Leslie: "Pathways regulating cytosolic phospholipase A2 activation and eicosanoid production in macrophages by Candida albicans." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30676-85, (2010) (PubMed).

Taylor, Reid, Heinsbroek, Brown, Gordon, Wong: "Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo." in: European journal of immunology, Vol. 35, Issue 7, pp. 2163-74, (2005) (PubMed).

Target Details

Target: C-Type Lectin Domain Family 6, Member A (CLEC6A)

Alternative Name: DECTIN-2 (CLEC6A Products)

Gene ID: 56620

UniProt: Q9JKF4