PLP1 antibody

Catalog No. ABIN2475779

The Mouse Monoclonal anti-PLP1 antibody has been validated for WB, FACS, IF, IHC (p) and IHC (fro). It is suitable to detect PLP1 in samples from Human, Rat, Cow, Dog, Mammalian, Pig and Marmoset. There are 3+ publications available.

Quick Overview for PLP1 antibody (ABIN2475779)

Target: PLP1 (Proteolipid Protein 1 (PLP1))

Reactivity: Human, Rat, Cow, Dog, Mammalian, Pig, Marmoset

Host: Mouse

Clonality: Monoclonal

Conjugate: This PLP1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: Plpc1

Product Details anti-PLP1 Antibody

Cross-Reactivity: Human

Characteristics: Purified IgG

Purification: Purified

Immunogen: A synthetic peptide GRGTKF corresponding to the C terminal region of the myelin proteolipid protein

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

References for anti-PLP1 antibody (ABIN2475779)

Hinson, Romero, Popescu, Lucchinetti, Fryer, Wolburg, Fallier-Becker, Noell, Lennon: "Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 4, pp. 1245-50, (2012) (PubMed).

van Horssen, Singh, van der Pol, Kipp, Lim, Peferoen, Gerritsen, Kooi, Witte, Geurts, de Vries, Peferoen-Baert, van den Elsen, van der Valk, Amor: "Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation." in: Journal of neuroinflammation, Vol. 9, pp. 156, (2012) (PubMed).

Rosetti, Maggio: "Protein-induced surface structuring in myelin membrane monolayers." in: Biophysical journal, Vol. 93, Issue 12, pp. 4254-67, (2007) (PubMed).

Target Details for PLP1

Target: PLP1 (Proteolipid Protein 1 (PLP1))

Alternative Name: MYELIN PROTEOLIPID PROTEIN

Background: Synonyms: PLP

Gene ID: 281410

UniProt: P04116