TIM3 antibody (AA 1-191)

Catalog No. ABIN2476818

Product Details anti-TIM3 Antibody

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Binding Specificity: AA 1-191

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This TIM3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Characteristics: Purified IgG

Purification: Purified

Immunogen: Tim-3-Ig, consisting of amino acids 1-191 of mouse Tim-3, coupled with the Fc portion of mouse IgG2a.

Clone: RMT3-23

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

References for anti-TIM3 antibody (ABIN2476818)

Nakayama, Akiba, Takeda, Kojima, Hashiguchi, Azuma, Yagita, Okumura: "Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation." in: Blood, Vol. 113, Issue 16, pp. 3821-30, (2009) (PubMed).

Oikawa, Kamimura, Akiba, Yagita, Okumura, Takahashi, Zeniya, Tajiri, Azuma: "Preferential involvement of Tim-3 in the regulation of hepatic CD8+ T cells in murine acute graft-versus-host disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 7, pp. 4281-7, (2006) (PubMed).

Target Details for TIM3

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Alternative Name: TIM-3 (TIM 3 Products)

Target Type: Virus

Background: Synonyms: T-CELL IMMUNOGLOBULIN MUCIN 3

Gene ID: 171285

UniProt: Q8VIM0

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints