WIPI2 antibody

Catalog No. ABIN2477140

This Mouse Monoclonal antibody specifically detects WIPI2 in WB, IP, IF and IHC (p). It exhibits reactivity toward Human and Mouse and has been mentioned in 3+ publications.

Quick Overview for WIPI2 antibody (ABIN2477140)

Target: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This WIPI2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2A2

Product Details anti-WIPI2 Antibody

Cross-Reactivity: Mouse (Murine)

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-WIPI2 antibody (ABIN2477140)

Dooley, Razi, Polson, Girardin, Wilson, Tooze: "WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1." in: Molecular cell, Vol. 55, Issue 2, pp. 238-52, (2014) (PubMed).

Karanasios, Stapleton, Manifava, Ktistakis: "Imaging autophagy." in: Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.], Vol. 69, pp. 12.34.1-12.34.16, (2014) (PubMed).

Polson, de Lartigue, Rigden, Reedijk, Urbé, Clague, Tooze: "Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation." in: Autophagy, Vol. 6, Issue 4, pp. 506-22, (2013) (PubMed).

Target Details for WIPI2

Target: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Alternative Name: Wipi2

Gene ID: 26100, 74781

UniProt: Q80W47, Q9Y4P8