C1q antibody (FITC)

Catalog No. ABIN2477784

This anti-C1q antibody is a Sheep Polyclonal antibody detecting C1q in IHC (fro). Suitable for Human. This Primary Antibody has been cited in 3+ publications.

Quick Overview for C1q antibody (FITC) (ABIN2477784)

Target: C1q (Complement Fragment C1q (C1q))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This C1q antibody is conjugated to FITC

Application: Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-C1q Antibody (FITC)

Characteristics: Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC)

Immunogen: Human C1q, purified from plasma

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 10 mg/mL

References for anti-C1q antibody (FITC) (ABIN2477784)

Hwang, Duvall, Tomlinson, Boackle et al.: "Highly specific inhibition of C1q globular-head binding to human IgG: a novel approach to control and regulate the classical complement pathway using an engineered single chain antibody variable ..." in: Molecular immunology, Vol. 45, Issue 9, pp. 2570-80, (2008) (PubMed).

Cragg, Glennie: "Antibody specificity controls in vivo effector mechanisms of anti-CD20 reagents." in: Blood, Vol. 103, Issue 7, pp. 2738-43, (2004) (PubMed).

Sárvári, Vágó, Wéber, Nagy, Gál, Mák, Kósa, Závodszky, Pázmány: "Inhibition of C1q-beta-amyloid binding protects hippocampal cells against complement mediated toxicity." in: Journal of neuroimmunology, Vol. 137, Issue 1-2, pp. 12-8, (2003) (PubMed).

Target Details for C1q

Target: C1q (Complement Fragment C1q (C1q))

Alternative Name: C1q

Background: Synonyms: COMPLEMENT COMPONENT 1q

Gene ID: 712, 713, 714

UniProt: P02745, P02746, P02747