PRNP antibody

Catalog No. ABIN2479379

The Mouse Monoclonal anti-PRNP antibody has been validated for ELISA and IHC (p). It is suitable to detect PRNP in samples from Sheep. There are 3+ publications available.

Quick Overview for PRNP antibody (ABIN2479379)

Target: PRNP (Prion Protein (PRNP))

Reactivity: Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: This PRNP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2G11

Product Details anti-PRNP Antibody

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-PRNP antibody (ABIN2479379)

Ortiz-Pelaez, Georgiadou, Simmons, Windl, Dawson, Arnold, Neocleous, Papasavva-Stylianou: "Allelic variants at codon 146 in the PRNP gene show significant differences in the risk for natural scrapie in Cypriot goats." in: Epidemiology and infection, Vol. 143, Issue 6, pp. 1304-10, (2015) (PubMed).

Andréoletti, Berthon, Levavasseur, Marc, Lantier, Monks, Elsen, Schelcher: "Phenotyping of protein-prion (PrPsc)-accumulating cells in lymphoid and neural tissues of naturally scrapie-affected sheep by double-labeling immunohistochemistry." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 50, Issue 10, pp. 1357-70, (2002) (PubMed).

Andréoletti, Berthon, Marc, Sarradin, Grosclaude, van Keulen, Schelcher, Elsen, Lantier: "Early accumulation of PrP(Sc) in gut-associated lymphoid and nervous tissues of susceptible sheep from a Romanov flock with natural scrapie." in: The Journal of general virology, Vol. 81, Issue Pt 12, pp. 3115-26, (2000) (PubMed).

Target Details for PRNP

Target: PRNP (Prion Protein (PRNP))

Alternative Name: CD230

Background: Synonyms: PRION PROTEIN

Gene ID: 493887

UniProt: P23907

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation