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CD28 antibody

Cited in 3+ publications. The Mouse Monoclonal anti-CD28 antibody (Clone E18) (ABIN2479686) specifically detects CD28 in FACS and Func. The antibody is reactive with Mouse samples.
Catalog No. ABIN2479686
-15% Promotion 2026
$787.42
$926.38
save $138.96 (-15 %)
Plus shipping costs $50.00
0.5 mg
Shipping to: United States
Delivery in 3 to 4 Business Days

Quick Overview for CD28 antibody (ABIN2479686)

Target

See all CD28 Antibodies
CD28

Reactivity

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  • 7
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Mouse

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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  • 1
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This CD28 antibody is un-conjugated

Application

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Flow Cytometry (FACS), Functional Studies (Func)

Clone

E18
  • Characteristics

    Purified IgG

    Endotoxin Level

    Low endotoxin

    Immunogen

    Alternate immunisation with A20 cells expressing mCD28 and recombinant mCD28Ig.

    Isotype

    IgG2b
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.0 mg/mL
  • Gogishvili, Lühder, Kirstein, Nieuwenhuizen, Goebbels, Beer-Hammer, Pfeffer, Reuter, Taube, Brombacher, Hünig: "Interruption of CD28-mediated costimulation during allergen challenge protects mice from allergic airway disease." in: The Journal of allergy and clinical immunology, Vol. 130, Issue 6, pp. 1394-403.e4, (2012) (PubMed).

    Beyersdorf, Ding, Blank, Dennehy, Kerkau, Hünig: "Protection from graft-versus-host disease with a novel B7 binding site-specific mouse anti-mouse CD28 monoclonal antibody." in: Blood, Vol. 112, Issue 10, pp. 4328-36, (2008) (PubMed).

    Dennehy, Elias, Zeder-Lutz, Ding, Altschuh, Lühder, Hünig: "Cutting edge: monovalency of CD28 maintains the antigen dependence of T cell costimulatory responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 10, pp. 5725-9, (2006) (PubMed).

  • Target

    CD28

    Alternative Name

    CD28

    Gene ID

    12487

    UniProt

    P31041

    Pathways

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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