KCNT1 antibody (AA 1168-1237) (Atto 488)

Catalog No. ABIN2482918

The Mouse Monoclonal anti-KCNT1 antibody is suitable to detect KCNT1 in samples from Rat. It has been validated for WB, IHC, ICC, IF and AA.

Quick Overview for KCNT1 antibody (AA 1168-1237) (Atto 488) (ABIN2482918)

Target: KCNT1 (Potassium Channel, Subfamily T, Member 1 (KCNT1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This KCNT1 antibody is conjugated to Atto 488

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Antibody Array (AA)

Clone: N3-26 (Formerly S3-26)

Product Details anti-KCNT1 Antibody (Atto 488)

Binding Specificity: AA 1168-1237

Specificity: Detects ~140 kDa. Weak human detection. Does not cross-react with KCNT2/Slo2.1/Slick.

Cross-Reactivity: Human, Mouse, Rat

Purification: Protein G Purified

Immunogen: Fusion protein amino acids 1168-1237 of rat Slo2.2 (Slack)

Isotype: IgG1

Application Details

Application Notes:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Comment:

1 μg/ml of ABIN2482918 was sufficient for detection of Slo2.2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Conjugated antibodies should be stored at 4°C

Target Details for KCNT1

Target: KCNT1 (Potassium Channel, Subfamily T, Member 1 (KCNT1))

Alternative Name: Slo2.2

Background: Slo2.2 is a novel member of the mammalian Slo potassium channel gene family. Slo2 channels may contribute to the resting potentials of cells that control their basal level of excitability (1). They also have sensors that couple channel activity to the intracellular concentrations of Na+ and Cl- (2).

Gene ID: 60444

NCBI Accession: NP_068625

UniProt: Q9Z258