Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2) (AA 20-120) antibody (HRP)

Catalog No. ABIN2559498

The Rabbit Polyclonal anti-Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 antibody is suitable to detect Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 in samples from Mouse. It has been validated for WB, ELISA, IHC (fro) and IHC (p).

Quick Overview for Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2) (AA 20-120) antibody (HRP) (ABIN2559498)

Target: Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 20-120

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRF2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2)

Alternative Name: GRF2

Background:

Synonyms: GRF2, RAS-GRF2, Ras-specific guanine nucleotide-releasing factor 2, Ras guanine nucleotide exchange factor 2, RASGRF2

Background: Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.

Gene ID: 5924

UniProt: O14827

Pathways: Neurotrophin Signaling Pathway