FIBIN antibody (AA 101-200) (Biotin)

Catalog No. ABIN2559631

Product Details anti-FIBIN Antibody (Biotin)

Target: FIBIN (Fin Bud Initiation Factor Homolog (FIBIN))

Binding Specificity: AA 101-200

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FIBIN antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FIBIN

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FIBIN

Target: FIBIN (Fin Bud Initiation Factor Homolog (FIBIN))

Alternative Name: FIBIN (FIBIN Products)

Background:

Synonyms: Fin bud initiation factor homolog, FIBIN, PSEC0235

Background: FIBIN (Fin bud initiation factor homolog) is a 211 amino acid protein involved in fin initiation in zebrafish. The human homolog is encoded by a gene that maps to chromosome 11, which makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and _ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Gene ID: 387758

UniProt: Q8TAL6