NANOS3 antibody (AA 101-173) (Biotin)

Catalog No. ABIN2559642

The Rabbit Polyclonal anti-NANOS3 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect NANOS3 in samples from Mouse.

Quick Overview for NANOS3 antibody (AA 101-173) (Biotin) (ABIN2559642)

Target: NANOS3 (Nanos Homolog 3 (NANOS3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NANOS3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NANOS3 Antibody (Biotin)

Binding Specificity: AA 101-173

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nanos3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NANOS3

Target: NANOS3 (Nanos Homolog 3 (NANOS3))

Alternative Name: Nanos3

Background:

Synonyms: NOS3, NANOS1L, Nanos homolog 3, NOS-3, NANOS3

Background: Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.

Gene ID: 342977

UniProt: P60323

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling