AS3MT antibody (AA 21-120) (HRP)

Catalog No. ABIN2559678

The Rabbit Polyclonal anti-AS3MT antibody has been validated for ELISA and WB. It is suitable to detect AS3MT in samples from Mouse.

Quick Overview for AS3MT antibody (AA 21-120) (HRP) (ABIN2559678)

Target: AS3MT (Arsenic (+3 Oxidation State) Methyltransferase (AS3MT))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AS3MT antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB)

Product Details anti-AS3MT Antibody (HRP)

Binding Specificity: AA 21-120

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CYT19

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for AS3MT

Target: AS3MT (Arsenic (+3 Oxidation State) Methyltransferase (AS3MT))

Alternative Name: CYT19

Background:

Synonyms: CYT19, Arsenite methyltransferase, Methylarsonite methyltransferase, S-adenosyl-L-methionine:arsenic(III) methyltransferase, AS3MT

Background: Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH (By similarity).

Gene ID: 57412

UniProt: Q9HBK9