CYB5R4 antibody (AA 21-120) (Cy5.5)

Catalog No. ABIN2559721

This anti-CYB5R4 antibody is a Rabbit Polyclonal antibody detecting CYB5R4 in WB, IF (cc) and IF (p). Suitable for Human, Rat and Mouse.

Quick Overview for CYB5R4 antibody (AA 21-120) (Cy5.5) (ABIN2559721)

Target: CYB5R4 (Cytochrome B5 Reductase 4 (CYB5R4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYB5R4 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CYB5R4 Antibody (Cy5.5)

Binding Specificity: AA 21-120

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CYB5R4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CYB5R4

Target: CYB5R4 (Cytochrome B5 Reductase 4 (CYB5R4))

Alternative Name: CYB5R4

Background:

Synonyms: NCB5OR, cb5/cb5R, dJ676J13.1, Cytochrome b5 reductase 4, Flavohemoprotein b5/b5R, b5+b5R, N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein, CYB5R4

Background: NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin.

Gene ID: 51167

UniProt: Q7L1T6

Pathways: Hormone Transport, Carbohydrate Homeostasis