CYB5R4 antibody (AA 21-120) (HRP)

Catalog No. ABIN2559725

This Rabbit Polyclonal antibody specifically detects CYB5R4 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CYB5R4 antibody (AA 21-120) (HRP) (ABIN2559725)

Target: CYB5R4 (Cytochrome B5 Reductase 4 (CYB5R4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYB5R4 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CYB5R4 Antibody (HRP)

Binding Specificity: AA 21-120

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CYB5R4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CYB5R4

Target: CYB5R4 (Cytochrome B5 Reductase 4 (CYB5R4))

Alternative Name: CYB5R4

Background:

Synonyms: NCB5OR, cb5/cb5R, dJ676J13.1, Cytochrome b5 reductase 4, Flavohemoprotein b5/b5R, b5+b5R, N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein, CYB5R4

Background: NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin.

Gene ID: 51167

UniProt: Q7L1T6

Pathways: Hormone Transport, Carbohydrate Homeostasis