CXCR4 antibody (PE)

Catalog No. ABIN2567293

Product Details anti-CXCR4 Antibody (PE)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CXCR4 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor.

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clone: 2B11

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Target Details for CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Alternative Name: CD184 (CXCR4 Products)

Background: The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor. It is expressed by astrocytes, B cells, T cells, monocytes, neutrophils, neurons, and hematopoietic cell types. CD184 is a coreceptor for X4 HIV-1.The monoclonal 2B11 antibody recognizes the amino terminus of CD184 and has functional activity.

Gene ID: 4041

UniProt: O75197

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events