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PD-1 antibody (FITC)

PDCD1 Reactivity: Human FACS Host: Mouse Monoclonal MIH4 FITC

Catalog No. ABIN2567415

Datasheet as PDF

Target See all PD-1 (PDCD1) Antibodies

PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
Reactivity
148

80

26

5

3

1
Human
Host
85

68

31

13

3

2

2

2

1
Mouse
Compatible Secondaries
Clonality
141

60

5
Monoclonal
Conjugate
111

13

12

10

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This PD-1 antibody is conjugated to FITC
Application
131

67

51

49

37

20

13

13

13

11

10

9

9

7

5

4

4

4

4

3

2

1

1

1

1

1
Flow Cytometry (FACS)

Specificity

The MIH4 monoclonal antibody specifically reacts with human Programmed death-1 (PD-1 or CD279), a 50-55 kDA glycoprotein.

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clone

MIH4

Isotype

IgG1 kappa

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Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage

4 °C

Storage Comment

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Alternative Name

CD279 (PDCD1 Products)

Background

The MIH4 monoclonal antibody specifically reacts with human Programmed death-1 (PD-1 or CD279), a 50-55 kDA glycoprotein. It is expressed on mainly on activated B, T, and myeloid cells. Within the cytoplasmic region, PD-1 contains an Immunoreceptor tyrosine-based inhibitory motif (ITIM) and seems to regulate peripheral tolerance. The lack or mutation of CD279 is linked to autoimmune disorders.

Gene ID

5133

UniProt

Q15116

Pathways

Cancer Immune Checkpoints