Integrin beta 3 antibody

Catalog No. ABIN2567873

This Hamster Monoclonal antibody specifically detects Integrin beta 3 in FACS and Func. It exhibits reactivity toward Mouse and Rat.

Quick Overview for Integrin beta 3 antibody (ABIN2567873)

Target: Integrin beta 3 (ITGB3)

Reactivity: Mouse, Rat

Host: Hamster

Clonality: Monoclonal

Conjugate: This Integrin beta 3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 2C9-G3

Product Details anti-Integrin beta 3 Antibody

Specificity: The 2C9.G3 monoclonal antibody specifically reacts with the mouse/rat CD61 Molecule, known as the integrin beta 3 that forms the vitronectin receptor with CD51.

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C. Do not freeze.

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: CD61

Background: The 2C9.G3 monoclonal antibody specifically reacts with the mouse/rat CD61 Molecule, known as the integrin beta 3 that forms the vitronectin receptor with CD51. The complex binds to other ligands such as fibrinogen, fibronectin, thrombospondin, and von WIllebrand factor. It is expressed by granulocytes, platelets, activated T cells, smooth muscle, and a subset of B cells.

Gene ID: 16416

UniProt: O54890

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex