IL-4 antibody

Catalog No. ABIN2568255

The Rat Monoclonal anti-IL-4 antibody has been validated for ELISA, IHC, FACS, IF and Func. It is suitable to detect IL-4 in samples from Mouse.

Quick Overview for IL-4 antibody (ABIN2568255)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Clone: 11B11

Product Details anti-IL-4 Antibody

Specificity: The 11B11 monoclonal antibody specifically reacts with mouse 14 kDa cytokine IL-4, expressed by the activated NKT cells and mast cells.

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C. Do not freeze.

Target Details for IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL-4

Background: The 11B11 monoclonal antibody specifically reacts with mouse 14 kDa cytokine IL-4, expressed by the activated NKT cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen.The 11B11 antibody neutralizes the IL-4 cytokine.

Gene ID: 16189

UniProt: P07750

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation