CCL2 antibody

Catalog No. ABIN2568348

The Hamster Monoclonal anti-CCL2 antibody has been validated for FACS, Neut and Func. It is suitable to detect CCL2 in samples from Human and Mouse.

Quick Overview for CCL2 antibody (ABIN2568348)

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reactivity: Human, Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CCL2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Neutralization (Neut), Functional Studies (Func)

Clone: 2H5

Product Details anti-CCL2 Antibody

Specificity: The 2H5 monoclonal antibody specifically reacts with mouse, rat, human MCP-1 (Monocyte Chemoattractant Protein-1), also known as CCL2 and MCAF (Monocyte Chemotactic and Activating Factor).

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C. Do not freeze.

Target Details for CCL2

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Alternative Name: MCP-1

Background: The 2H5 monoclonal antibody specifically reacts with mouse, rat, human MCP-1 (Monocyte Chemoattractant Protein-1), also known as CCL2 and MCAF (Monocyte Chemotactic and Activating Factor). MCP-1 is a C-C (beta) chemokine that regulates cytokine production in monocytes and the expression of adhesion molecules. The 2h5 antibody can neutralize the bioactivity of recombinant or natural MCP-1.

Gene ID: 6347, 20296

UniProt: P13500, P10148

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection