PLD1 antibody (pThr147)
Quick Overview for PLD1 antibody (pThr147) (ABIN2568437)
Target
See all PLD1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pThr147
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Specificity
- The antibody detects endogenous levels of PLD1 only when phosphorylated at threonine 147.
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Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- PLD1 (phospho Thr147) antibody was raised against a peptide sequence around phosphorylation site of threonine 147 (R-H-T (p)-F-R) derived from Human PLD1.
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Isotype
- IgG
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Application Notes
- Western Blot: 1:500~1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store antibody at -20°C for up to one year.
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- PLD1 (Phospholipase D1 (PLD1))
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Alternative Name
- PLD1
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Background
- Phosphatidylcholine (PC)-specific phospholipases D (PLDs, EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis.
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Molecular Weight
- 120 kDa
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Gene ID
- 5337
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NCBI Accession
- NP_002653
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UniProt
- Q13393
Target
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