GAPDH antibody
Quick Overview for GAPDH antibody (ABIN2621170)
Target
See all GAPDH AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Brand
- IHC-plus™
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Specificity
- Recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyze the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin.
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Purification
- Protein A purified
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Immunogen
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Rabbit muscle GAPDH.
Type of Immunogen: Purified protein -
Isotype
- IgG1
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Application Notes
- Approved: ELISA, IF, IHC, IHC-Fr, IHC-P (10 μg/mL), IP, WB
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Comment
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Target Species of Antibody: Rabbit
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C,-20 °C
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Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
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Alternative Name
- GAPDH
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Background
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Name/Gene ID: GAPDH
Synonyms: GAPDH, A1 40 kd subunit, Activator 1 40 kd subunit, G3PD, GAPD, G3pdh, Rfc40, Rf-c 40 kd subunit -
Gene ID
- 2597
Target
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