Growth Hormone 1 antibody

Catalog No. ABIN263750

The Mouse Monoclonal anti-Growth Hormone 1 antibody has been validated for EIA. It is suitable to detect Growth Hormone 1 in samples from Human.

Quick Overview for Growth Hormone 1 antibody (ABIN263750)

Target: Growth Hormone 1 (GH1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Growth Hormone 1 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: 090-12610

Product Details anti-Growth Hormone 1 Antibody

Specificity: This antibody reacts to Growth Hormone (HGH). Crossreactivity: Human Placental Lactogen: 0.02 % Human Prolactin: 0.02 %Aff. Const.:1.0 x 10e10 L/m

Characteristics: Synonyms: Pituitary growth hormone, Growth hormone 1, HGH

Purification: Protein A chromatography

Purity: > 90 % pure (SDS-PAGE)

Immunogen: HGH isolated from human pituitary gland

Isotype: IgG1

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 5.2mg/mL (OD280nm, E0.1% = 1.4)

Buffer: 10 mM Phosphate, pH 7.4 containing 150 mM Sodium chloride and 0,09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one week or (in aliquots) at -40 °C for longer. If aliquoted for long term storage, fill volume should be equal to or greater than 50% of thenominal fill volume of the vial used. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Alternative Name: Somatotropin / Growth Hormone / GH1

Background: Human growth hormone (hGH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. The effects of hGH in the body can be generally described as anabolic. It stimulates amino acid uptake and protein synthesis in muscle and other tissues. Growth Hormone (GH1) is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Genes for growth hormone (GH) are found in a gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. The GHN1 gene is transcribed exclusively in the pituitary, whereas the other 4 genes are expressed only in placental tissues. Several isoforms of GH1 exist.Synonyms: Growth hormone 1, HGH, Pituitary growth hormone

Gene ID: 2688

UniProt: P01241

Pathways: NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process