HBSAg antibody (Subtype ad/ay)
Quick Overview for HBSAg antibody (Subtype ad/ay) (ABIN263770)
Target
See all HBSAg (HBsAg) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- Subtype ad/ay
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Virus Strain
- Subtype ad/ay
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Characteristics
- Synonyms: HBV Large envelope protein, L glycoprotein, Large S protein, Large surface protein, HBVMajor surface antigen
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Purification
- Protein A Chromatography.
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Immunogen
- Purified HBsAg subtypes ad and ay
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Isotype
- IgG2a
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Application Notes
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ELISA: Use this antibody as Detection and ABIN263768 as Capture antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 5.72 mg/mL (OD280nm, E0.1% = 1.4)
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Buffer
- 10 mM Phosphate, pH 7.4 containing 150 mM Sodium Chloride and 0.05 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C for one week or (in aliquots) at -40 °C for longer. If aliquoted for long term storage, fill volume should be equal to or greater than 50% of thenominal fill volume of the vial used. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Expiry Date
- 12 months
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- HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))
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Alternative Name
- Hepatitis B Surface Antigen / HBsAg
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Target Type
- Viral Protein
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Background
- Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.Synonyms: HBV surface antigen, Hepatitis B Virus
Target
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