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alpha-Thrombin antibody

This anti-alpha-Thrombin antibody is a Mouse Monoclonal antibody detecting alpha-Thrombin in EIA. Suitable for Human.
Catalog No. ABIN264120

Quick Overview for alpha-Thrombin antibody (ABIN264120)

Target

alpha-Thrombin

Reactivity

  • 11
  • 3
  • 3
Human

Host

  • 9
  • 7
  • 1
Mouse

Clonality

  • 16
  • 1
Monoclonal

Conjugate

  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
This alpha-Thrombin antibody is un-conjugated

Application

  • 10
  • 8
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Enzyme Immunoassay (EIA)

Clone

BDI905
  • Purification

    Ammonium sulfate precipitation, ion-exchange chromatography and gel filtration

    Purity

    > 95 % pure (SDS-PAGE)

    Immunogen

    Purified human thrombin

    Isotype

    IgG1
  • Application Notes

    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    4.4mg/mL (OD280nm, E1% = 14)

    Buffer

    50 % Glycerol/water (vol/vol)

    Storage

    -20 °C

    Storage Comment

    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    Expiry Date

    12 months
  • Target

    alpha-Thrombin

    Alternative Name

    Thrombin

    Background

    Thrombin is an active enzyme in the earliest steps of the blood clot formation, generated from its circulating inactive precursor prothrombin. Thrombin is a glycoprotein formed by two peptides chains of 36 and 259 amino acids linked by disulfure bonds. Three important sites have been identified on the surface of the enzyme: The catalytic site that confers to the molecule its serine protease activity, the exosite one responsible for the binding of the substrate (fibrinogen or thrombin receptor) and the exosite two responsible for the binding of antithrombin III and inactivation of thrombin. The molecular mass of thrombin is 37 kDa.
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