NPDC1 antibody

Catalog No. ABIN264467

Product Details anti-NPDC1 Antibody

Target: NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This NPDC1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody react to NPDC-1.

Characteristics: Synonyms: NPDC-1, Neural proliferation differentiation and control protein 1

Purification: Purified

Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with a syntheticpeptide derived from human NPDC-1 protein and mouse myeloma cells.

Clone: 1-60E-005

Isotype: IgG1

Application Details

Application Notes: Western Blot: 1: 1000. Positive Control: Brain tissue lysate (mouse and rat tested, human not yet tested).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: 20 mM sodium phosphate, 150 mM sodium chloride, 50 % glycerol, pH 7.5, 3 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: The antibody can be shipped at 2-8 °C. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for NPDC1

Target: NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))

Alternative Name: NPDC1 (NPDC1 Products)

Background: The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptiona levents mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.Synonyms: NPDC-1, Neural proliferation differentiation and control protein 1

Gene ID: 56654

UniProt: Q9NQX5