Renin antibody

Catalog No. ABIN264819

This anti-Renin antibody is a Sheep Polyclonal antibody detecting Renin in WB, IHC (p) and EIA. Suitable for Rat and Mouse.

Quick Overview for Renin antibody (ABIN264819)

Target: Renin (REN)

Reactivity: Rat, Mouse

Host: Sheep

Clonality: Polyclonal

Conjugate: This Renin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Renin Antibody

Specificity: This antibody reacts with Renin.

Purification: Protein G Chromatography.

Immunogen: Recombinant Rat Prorenin

Application Details

Application Notes: ELISA: 1/50,000. Western blot: 1/5,000. Immunohistochemistry: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 8.7 mg/mL ((OD280nm, E0.1% = 1.36)

Buffer: 0.05 M Sodium Phosphate, 0.5 M Sodium Chloride, 1 mM EDTA, pH 6.6 without preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -80 °C

Target Details for Renin

Target: Renin (REN)

Alternative Name: Renin

Background: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Renin also occurs in other organs than the kidney, e.g., in the brain, where it is implicated in the regulation of numerous activities.Synonyms: Angiotensinogenase, HNFJ2, REN, angiotensin-forming enzyme

Gene ID: 5972

NCBI Accession: NP_000528

UniProt: P00797

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour