PPP2CA antibody

Catalog No. ABIN264947

The Sheep Polyclonal anti-PPP2CA antibody has been validated for WB and IP. It is suitable to detect PPP2CA in samples from Human, Mouse, Rat and Cow.

Quick Overview for PPP2CA antibody (ABIN264947)

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Reactivity: Human, Mouse, Rat, Cow

Host: Sheep

Clonality: Polyclonal

Conjugate: This PPP2CA antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PPP2CA Antibody

Specificity: This antibody reacts to serine/threonine protein phosphatase 2A/C.

Purification: Purified

Isotype: IgG

Application Details

Application Notes: Immunoblotting: 1: 500 to 1: 1,000. Immunoprecipitation often used in combination with affinity purified anti-pp2A/A toimmunoprecipitate hetrotrimeric pp2A. Immunocytochemistry 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for PPP2CA

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Alternative Name: PPP2CA

Background: The immunogen used to the purified peptide conjugated to KLH corresponding to the sequence NH2-Pro-His-Val-Thr-Arg-Arg-Thr-Pro-Asp-Tyr-Phe-Leu-COOH. This peptide antibody corresponds to C -terminal peptide of PP2A/C catalytic subunit having a MW of 36 kDa. The sequence used is amino acid 298 - 309.Synonyms: PP2A-alpha, Protein Phospatase 2A, Replication protein C, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

Gene ID: 5515

NCBI Accession: NP_002706

UniProt: P67775

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades