FOSL2 antibody
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- Target See all FOSL2 Antibodies
- FOSL2 (FOS-Like Antigen 2 (FOSL2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FOSL2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody detects endogenous levels of Fra-2/FOSL2 protein. (region surrounding Ser301)
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Purity
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product FOSL2 Primary Antibody
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- Application Notes
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- FOSL2 (FOS-Like Antigen 2 (FOSL2))
- Alternative Name
- Fos-Related Antigen 2 (FOSL2 Products)
- Synonyms
- FOSL2 antibody, FRA2 antibody, Fra-2 antibody, Fra2 antibody, fra2 antibody, wu:fl17h04 antibody, xx:fl17h04 antibody, zgc:158347 antibody, PLB1 antibody, fra-2 antibody, FOS like 2, AP-1 transcription factor subunit antibody, fos-like antigen 2 antibody, FOSL2 antibody, Fosl2 antibody, fosl2 antibody
- Background
- The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70 % homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B, which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.Synonyms: FOSL2, FRA-2, FRA2
- Molecular Weight
- approx. 42 kDa
- Gene ID
- 2355
- NCBI Accession
- NP_005244
- UniProt
- P15408
- Pathways
- Feeding Behaviour, Photoperiodism
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