ITGAL antibody (APC)

Catalog No. ABIN2656893

This Rat Monoclonal antibody specifically detects ITGAL in FACS, WB and IHC. It exhibits reactivity toward Mouse.

Quick Overview for ITGAL antibody (APC) (ABIN2656893)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGAL antibody is conjugated to APC

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC)

Clone: H155-78

Product Details anti-ITGAL Antibody (APC)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: CD11a/CD18

Background: Lymphocyte function-associated antigen 1 or LFA-1 is a heterodimer composed of two members of the integrin family, αL (CD11a) and β2 (CD18). LFA-1 is expressed primarily on lymphocytes, monocytes/macrophages, and granulocytes. It is involved in cell adhesion and costimulation processes. The ligands for LFA-1 are ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

Pathways: Activated T Cell Proliferation, Integrin Complex