IRF4 antibody (Alexa Fluor 488)

Catalog No. ABIN2657086

The Rat Monoclonal anti-IRF4 antibody has been validated for FACS. It is suitable to detect IRF4 in samples from Human and Mouse.

Quick Overview for IRF4 antibody (Alexa Fluor 488) (ABIN2657086)

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IRF4 antibody is conjugated to Alexa Fluor 488

Application: Flow Cytometry (FACS)

Clone: IRF4-3E4

Product Details anti-IRF4 Antibody (Alexa Fluor 488)

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for IRF4

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Alternative Name: IRF4

Background: The IRF family consists of at least nine members. IRF4 and IRF8 are highly homologous to each other and also redundant in function. IRF4 is critical for Th2 and Th17 development. Together with TRF8, it plays an essential role in macrophage and dendritic cell development and function. IRF4 is also reported to be essential for pre-B cell development, receptor editing, germinal center reactor and plasma cell differentiation.

Pathways: Chromatin Binding