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MCAM antibody (Alexa Fluor 647)

The Mouse Monoclonal anti-MCAM antibody has been validated for FACS. It is suitable to detect MCAM in samples from Human.
Catalog No. ABIN2657131

Quick Overview for MCAM antibody (Alexa Fluor 647) (ABIN2657131)

Target

See all MCAM Antibodies
MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Reactivity

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  • 55
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  • 2
Human

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This MCAM antibody is conjugated to Alexa Fluor 647

Application

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Flow Cytometry (FACS)

Clone

P1H12
  • Cross-Reactivity (Details)

    Mouse, Canine2, 5, Rabbit

    Purification

    The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

    Isotype

    IgG1 kappa
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Protect from prolonged exposure to light. Do not freeze.

    Storage

    4 °C

    Storage Comment

    The antibody solution should be stored undiluted between 2°C and 8°C
  • Target

    MCAM (Melanoma Cell Adhesion Molecule (MCAM))

    Alternative Name

    CD146

    Background

    CD146 is a 118 kD integral transmembrane glycoprotein that is also known as MUC18, S-Endo, MCAM, and Mel-CAM (melanoma cell adhesion molecule). It belongs to the immunoglobulin superfamily. CD146 is expressed on melanoma cells, epithelial cells, endothelial cells, fibroblasts, activated T cells, multipotent mesenchymal stromal cells, and activated keratinocytes. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration. The ligand of CD146 remains to be identified.
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