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Neuropilin 1 antibody (Alexa Fluor 647)

This Mouse Monoclonal antibody specifically detects Neuropilin 1 in IP and FACS. It exhibits reactivity toward Human.
Catalog No. ABIN2657169

Quick Overview for Neuropilin 1 antibody (Alexa Fluor 647) (ABIN2657169)

Target

See all Neuropilin 1 (NRP1) Antibodies
Neuropilin 1 (NRP1)

Reactivity

  • 116
  • 66
  • 57
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 124
  • 31
  • 4
  • 3
  • 1
Mouse

Clonality

  • 117
  • 46
Monoclonal

Conjugate

  • 86
  • 22
  • 16
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neuropilin 1 antibody is conjugated to Alexa Fluor 647

Application

  • 125
  • 69
  • 47
  • 40
  • 35
  • 28
  • 15
  • 14
  • 13
  • 10
  • 4
  • 4
  • 1
  • 1
Immunoprecipitation (IP), Flow Cytometry (FACS)

Clone

12C2
  • Purification

    The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

    Isotype

    IgG2a kappa
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Protect from prolonged exposure to light. Do not freeze.

    Storage

    4 °C

    Storage Comment

    The antibody solution should be stored undiluted between 2°C and 8°C
  • Target

    Neuropilin 1 (NRP1)

    Alternative Name

    CD304

    Background

    CD304, also known as neuropilin-1, BDCA-4 and VEGF165R, is a 140 kD type I transmembrane protein. Its extracellular region contains 2 CUB, 2 FV/FVIII, and one MAM domain, a soluble isoform is produced by alternative mRNA splicing. CD304 is involved in angiogenesis, neural development, and tumor metastasis. It's expressed by plasmacytoid dendritic cells, thymocytes, neurons, endothelium, and a subset of TFH cells. CD304 is also expressed in several carcinomas, and a high expression of this molecule in prostate cancer correlates with a poor prognosis.

    Pathways

    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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