Cytokeratin 19 antibody (Alexa Fluor 647)
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- Target See all Cytokeratin 19 (KRT19) Antibodies
- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Cytokeratin 19 antibody is conjugated to Alexa Fluor 647
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Application
- Flow Cytometry (FACS), Blocking Reagent (BR), Functional Studies (Func)
- Purification
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
- Clone
- A53-B-A2
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product KRT19 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C
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- Target
- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
- Alternative Name
- Cytokeratin 19 (KRT19 Products)
- Background
- Cytokeratin 19, also known as keratin 19, is a type I intermediate filament protein with a molecular weight of approximately 40-44 kD. Cytokeratin 19 is a heterotetramer composed of two type I and two type II keratin subunits. Unlike other cytokeratins, cytokeratin 19 lacks a C-terminal non-helical extension. This cytokeratin is widely expressed in the periderm (transient superficial layer enveloping developing epidermis), muscle, intestine, bile duct, esophagus, stomach, and thymus. Cytokeratin 19 can be upregulated by vitamin A and is thought to play a critical role in embryogenesis. Cytokeratin 19 intereacts with the pinin protein and has been shown to be modified by phosphorylation (Ser10, Ser35).
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