ITGAL antibody (Alexa Fluor 488)

Catalog No. ABIN2657311

The Mouse Monoclonal anti-ITGAL antibody has been validated for FACS and ICFC. It is suitable to detect ITGAL in samples from Human.

Quick Overview for ITGAL antibody (Alexa Fluor 488) (ABIN2657311)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGAL antibody is conjugated to Alexa Fluor 488

Application: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Clone: HI111

Product Details anti-ITGAL Antibody (Alexa Fluor 488)

Cross-Reactivity: Chimpanzee, Baboon, Capuchin Monkey, Horse (Equine), Cow (Bovine), Sheep (Ovine), Dog (Canine), Rabbit

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: CD11a

Background: CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

Pathways: Activated T Cell Proliferation, Integrin Complex