CD1c antibody (Alexa Fluor 488)

Catalog No. ABIN2657358

This Mouse Monoclonal antibody specifically detects CD1c in ELISA (Capture). It exhibits reactivity toward Human.

Quick Overview for CD1c antibody (Alexa Fluor 488) (ABIN2657358)

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD1c antibody is conjugated to Alexa Fluor 488

Application: ELISA (Capture)

Clone: L161

Product Details anti-CD1c Antibody (Alexa Fluor 488)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CD1c

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Alternative Name: CD1c

Background: CD1c, also known as R7 or M241, is a 43 kD member of the five CD1 antigens (CD1a-e) in humans. The CD1 Molecules are type I glycoprotein with structural similarities to MHC class I and are non-covalently associated with β2-microglobulin, belonging to the Ig superfamily. CD1c is expressed on cortical thymocytes, Langerhans cells, dendritic cells, and a subset of B cells. It has been reported that CD1c is also expressed on mature T cells in a tightly regulated manner. CD1c is involved in antigen-presentation of glycolipids. It may also act in T cells as an immune regulatory molecule.