CD43 antibody (Alexa Fluor 647)
Quick Overview for CD43 antibody (Alexa Fluor 647) (ABIN2657789)
Target
See all CD43 (SPN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purification
- The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
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Isotype
- IgG1 kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
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Storage
- 4 °C
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Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C
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- CD43 (SPN) (Sialophorin (SPN))
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Alternative Name
- CD43
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Background
- CD43, also known as Ly-48, Leukosialin, Sialophorin, Leukocyte Sialoglycoprotein, and W3/13, is a large single chain of type I transmembrane glycoprotein with abundant O-glycosylation and sialylation sites. It has been reported that CD43 binds to CD54 and Siglec-1. CD43 plays dual roles in cell adhesion and anti-adhesion, as well as costimulation of T cell activation and survival, and induction of apoptosis of T cells and hematopoietic progenitors.
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Pathways
- Regulation of Leukocyte Mediated Immunity
Target
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