Podoplanin antibody (Alexa Fluor 647)

Catalog No. ABIN2657994

This Rat Monoclonal antibody specifically detects Podoplanin in FACS. It exhibits reactivity toward Human.

Quick Overview for Podoplanin antibody (Alexa Fluor 647) (ABIN2657994)

Target: Podoplanin (PDPN)

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This Podoplanin antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS)

Clone: NC-08

Product Details anti-Podoplanin Antibody (Alexa Fluor 647)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG2a lambda

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for Podoplanin

Target: Podoplanin (PDPN)

Alternative Name: Podoplanin

Background: Podoplanin is a 40-43 kD type-I transmembrane sialomucin-type glycoprotein, also known as T1a, gp36, gp38, gp40, and Aggrus. Originally detected on the surface of podocytes, futher characterization showed podoplanin has a broad tissue distribution, including mesothelial cells, epithelial cells, follicular dendritic cells, and a variety of tumor cells. It has been reported that podoplanin is the ligand of CLEC2 and is involved in lymphatic vessel formation, platelet aggregation, and tumor metastasis. Podoplanin may serve as a useful marker for tumor diagnosis and prognosis.

Pathways: Dicarboxylic Acid Transport